Publications

Selected Academic Peer Reviewed Publications

Chiral glycine cation equivalents: N-acyliminium species derived from diketopiperazines. , Bull, S. D.Davies, S. G.; Garner, A. C.; O’Shea, M. D.; Savory, E. D.; Snow, E. J.  J. Chem. Soc., Perkin Trans. 1. 2002, (22), 2442. PDF Icon (254kb)

Conjugate additions of organocuprates to a 3-methylene-6-isopropyldiketopiperazine acceptor for the asymmetric synthesis of homochiral β-amino acids. ,  Bull, S. D.Davies, S. G.; Garner, A. C.; O’Shea, M. D. J. Chem. Soc., Perkin Trans. 1. 2001, (24), 3281. PDF Icon (139kb)

Stereoselective conjugate addition of organocuprates to a dehydroalanine derived diketopiperazine. , Bull, S. D.Davies, S. G.;O’Shea, M. D. J. Chem. Soc., Perkin Trans. 1. 1998, (22), 3657. PDF Icon (141kb)

Synthetic approaches to the Angucyclinone antibiotics: A concise entry to the ring system of PD 116740 and TAN 1085. , Larsen, D. S.O’Shea, M. D. J. Org. Chem. 1996, (61), 5681.  PDF Icon (200kb) and, for supporting information, PDF Icon (329kb)

Total syntheses of the Angucyclinone antibiotics (+) Emycin A and (+) Ochromycinone. , Brooker, S.Larsen, D. S.O’Shea, M. D.Chem Commun. 1996, 203. PDF Icon (276kb)

Synthetic approaches to the Angucyclinone antibiotics: The total synthesis of (±) Rubiginone B1 and B2, (±) Emycin A, and related analogues. , Larsen, D. S.O’Shea, M. D. J. Chem. Soc., Perkin Trans. 1. 1995, 1019. PDF Icon (1540kb)

A stereoselective approach to the Angucyclinone antibiotics: A total synthesis of (±) Rubiginone B1. , Larsen, D. S.O’Shea, M. D.Tetrahedron Lett. 1993, (34), 3679.

A stereoselective approach to the Angucyclinone antibiotics: A total synthesis of the C-1 epimer of (±) Rubiginone B1. , Larsen, D. S.O’Shea, M. D. Tetrahedron Lett. 1993, (34), 1373.

International Conference Presentations

A Software System for Automated HTA in Heterogeneous Empower, ChemStation, and MassLynx Controlled Analytical Systems Using a Single Common User Interface., 2008, see Consult-igma or Tessella for the Chromatographic Society abstract for this lecture.

Development and Implementation of an Informatics Solution to Enable Analytical Quality By Design (AQbD) LC Methods Development , see PittCon 2013 abstract